Arun Radhakrishnan, Gowthamarajan Kuppusamy* and Thirumalai Subramaniam K J*
Advances in personalized medicine are currently impacting positive improvement in the field of metabolic diseases and patient care. The current innovations in integrating nanotechnology & nanobiotechnology tools in pharmaceutical formulation development have proven effectiveness of xenobiotics for diagnosis, treatment and cure of various metabolic diseases. The implementation of nanomedicines for the treatment of metabolic diseases have served the advantage of overcoming the limitation of bioavailability, selectivity & specificity, biological barriers and toxicity. Simultaneously, hybridization of drug molecules and nanomaterials build promising effective tools for the same. While on the other hand, the development in omics sciences has further supported in the detection, diagnoses and treatment of various metabolic disease conditions. Therapy and analysis of metabolic diseases in asymptomatic patients, harsh complications in diagnosis, disease progression are facilitated by the use of molecular metabolic & genetic biomarkers, biosensor miniatures and transducers. Therefore, the merge in the concept of personalized medicine and nanotechnology gives rise and serves an ultimate goal of predicting, preventing and treating metabolic diseases. The current article reviews the interdisciplinary nature of the personalized medicine, nanotechnology and nanobiotechnology to employ safe, efficient, stable, cost effective, the futuristic approach for the individualized treatment strategies & challenges in application of personalized medicines for metabolic diseases.
Personalized Medicines, nanomedicines, nano tools, metabolic disease therapy, biomarkers, biosensors
Department of Pharmaceutics, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Ooty, Nilgiris, Tamil Nadu, Center of Excellence in Nano Science & Technology, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Ooty, Nilgiris, Tamil Nadu, Department of Pharmaceutics, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Ooty, Nilgiris, Tamil Nadu